"You will need an MS-DOS emulator to run Epi Info 6 if you're using the 64-bit versions of Windows Vista or Windows 7, as those operating systems no longer include support for MS-DOS programs. Epi Info 6 usually works fine on the 32-bit…"
According to Epi Info HelpDesk:
"EPI INFO 6 AND 64-BIT VERSIONS OF WINDOWSEpi 6, by default, will not run under Windows Vista or Windows 7 64-bit. This is because Vista 64 and Windows 7 64 only have support for 32-bit and 64-bit…"